Haemodynamic effects of initial combination therapy in pulmonary arterial hypertension: a systematic review and meta-analysis

Haemodynamic effects of initial combination therapy in pulmonary arterial hypertension: a systematic review and meta-analysis

New publication from the George Giannakoulas team in ERJ Open Research!Elena Vrana Sophia-Anastasia Mouratoglou Stefanos M. Zafeiropoulos Stavros Zanos.Thank you from the Greek patients with PAH!!! Read more in the link below: Haemodynamic effects of initial...
Sotatercept: ελπιδοφόρα αποτελέσματα ανακοίνωσε η MSD για τη θεραπεία της ΠΑΥ

Sotatercept: ελπιδοφόρα αποτελέσματα ανακοίνωσε η MSD για τη θεραπεία της ΠΑΥ

Σημαντική ανακοίνωση έκανε η MSD (MERCK) τη Δευτέρα 10 Οκτωβρίου, σχετικά με τις δοκιμές θεραπείας της Πνευμονικής Αρτηριακής Υπέρτασης (ΠΑΥ) με τη χρήση της πρωτεΐνης Sotatercept. Σύμφωνα με όσα έγιναν γνωστά, στην τρίτη φάση δοκιμών μιας θεραπείας σε 320 ενήλικες...
Prognostic of significance of cardio-ankle vascular index in new diagnosed idiopathic pulmonary hypertension

Prognostic of significance of cardio-ankle vascular index in new diagnosed idiopathic pulmonary hypertension

In previous studies, the cardio-ankle vascular index (CAVI) was increased significantly in idiopathic pulmonary arterial hypertension (IPAH) patients compared with the healthy group and did not differ much from that in systemic hypertensives. In this study, the...
Increased bone morphogenetic protein 10 activity is associated with increased right atrial wall stress and disease severity in precapillary pulmonary hypertension

Increased bone morphogenetic protein 10 activity is associated with increased right atrial wall stress and disease severity in precapillary pulmonary hypertension

Background: Pulmonary hypertension (PH) is characterized by increased right atrial (RA) stretch and pressure. The major genetic predisposing risk factor for PH involves mutations in bone morphogenetic protein (BMP) receptor 2 (BMPR2), for which BMP9 and BMP10 are...
Oxygenated hemoglobin as prognostic marker among patients with systemic sclerosis screened for pulmonary hypertension

Oxygenated hemoglobin as prognostic marker among patients with systemic sclerosis screened for pulmonary hypertension

Background: Oxygenated hemoglobin (OxyHem) in arterial blood may reflect disease severity in patients with systemic sclerosis (SSc), particularly among those with pulmonary manifestations, such as pulmonary hypertension (PH). Objectives: Hence, the aim of this study...
Increase in progenitor endothelial cells associated to right heart failure in pediatric patients with secondary pulmonary arterial hypertension

Increase in progenitor endothelial cells associated to right heart failure in pediatric patients with secondary pulmonary arterial hypertension

Background: Pulmonary arterial hypertension (PAH) is a serious condition that causes right heart failure. A persistent inflammatory process is present in the vascular endothelial tissue, which releases circulating CD34+,133+ endothelial progenitor cells (EPCs),...
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